Calmwise™ Serum

A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
A brown glass dropper bottle of Calmwise Serum is featured. Three bullet points with checkmarks list benefits: Visibly calms redness & helps to relieve sensitivity, Helps to improve skin barrier function against external irritants, and Leaves skin feeling nourished & comforted.
Close-up of an open amber glass bottle of Medik8 Calmwise Serum tipped on its side, pouring a pool of liquid onto a light surface. Text highlights key ingredients: Teprenone (helps strengthen the skin’s protective barrier against sensitivity) and Organic Sage Extract (helps soothe skin while protecting it against external irritants).
A glass dropper dispenses a single clear droplet of Calmwise Serum onto the palm of a hand, highlighting its lightweight, oil-free texture against a clean white background.
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin C (C-Tetra), and Sunscreen (Advanced Day Ultimate Protect). The PM routine involves Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin A (Crystal Retinal), and Moisturise (Advanced Night Restore).
A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
A brown glass dropper bottle of Calmwise Serum is featured. Three bullet points with checkmarks list benefits: Visibly calms redness & helps to relieve sensitivity, Helps to improve skin barrier function against external irritants, and Leaves skin feeling nourished & comforted.
Close-up of an open amber glass bottle of Medik8 Calmwise Serum tipped on its side, pouring a pool of liquid onto a light surface. Text highlights key ingredients: Teprenone (helps strengthen the skin’s protective barrier against sensitivity) and Organic Sage Extract (helps soothe skin while protecting it against external irritants).
A glass dropper dispenses a single clear droplet of Calmwise Serum onto the palm of a hand, highlighting its lightweight, oil-free texture against a clean white background.
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin C (C-Tetra), and Sunscreen (Advanced Day Ultimate Protect). The PM routine involves Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin A (Crystal Retinal), and Moisturise (Advanced Night Restore).
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Redness & sensitive skin

Calmwise™ Serum

  • Calm
  • |
  • Strengthen
  • |
  • Support
Soothing Elixir for Redness-Prone Skin
Visibly calm redness and relieve sensitive skin with Calmwise serum.

Formulated with teprenone (a patented anti-redness active), this lightweight serum helps to combat various kinds of redness by improving the skin's barrier function.

Redness caused by the likes of dryness, irritants and environmental stressors is visibly reduced while the complexion is left feeling nourished and comforted.
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An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
Total Moisture Daily Facial Cream™
  • Hydrate
  • |
  • Plump
  • |
  • Support
 AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Select a Size
Key Benefits
Visible Redness Reduction

Calmwise Serum's key ingredient, teprenone, has been found to visibly reduce skin redness in 1 month.*

*Independent trial by Sederma

Comfortable, Visibly Restored Skin

The fragrance-free formula won't aggravate irritated skin further but, instead, leaves it feeling calm, comfortable and visibly restored.

Skin Barrier Support

Helps to strengthen the skin's barrier function against the redness-inducing effects of moisture loss and environmental stressors.

How to Use

Step 1

If you’re new to Calmwise Serum, we advise performing a patch test at least 24 hours before first use. Learn how to patch test here

After cleansing in the morning and evening, massage 6 drops across the face where required.

Step 2

Leave to absorb before applying a moisturiser.

Step 3

Follow with a sunscreen in the morning.

Uses per bottle

75
Guide to Layering
Step 1: Cleanse
Medik8 Calmwise Soothing Cleanser pump bottle displayed on a white background with a smear of white foam behind it, highlighting the product's texture.
Morning
Evening
Calmwise™ Soothing Cleanser
Select a Size
Step 2: Target
A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
Morning
Evening
Calmwise™ Serum
(0)
Step 3: Brighten
Medik8 C-Tetra Advanced bottle displayed on a clean white background with translucent serum droplets, highlighting its lightweight gel-serum texture.
Morning
C-Tetra® Advanced
(0)
Step 4: Renew
Crystal Retinal®
Evening
Crystal Retinal®
Select a Strength
Step 5: Moisturise
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a
Morning
Evening
Total Moisture Daily Facial Cream™
Select a Size
Key Ingredients
Teprenone

A patented active that helps to soothe visible redness while supporting the skin barrier against external irritants.

Organic Sage Extract

A powerful, natural antioxidant that helps to protect skin against irritating external stressors. It also possesses anti-inflammatory properties to help calm both the look and feel of redness-prone skin.

Full List of Ingredients
Calmwise™ Serum
Soothing Elixir for Redness-Prone Skin

Simmondsia Chinensis (Jojoba) Seed Oil, Cyclopentasiloxane, Cyclohexasiloxane, Caprylic/Capric Triglyceride, Tocopheryl Acetate, Teprenone, Salvia Officinalis (Sage) Extract.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • No artificial fragrance
  • No synthetic colours
  • Paraben free
  • Alcohol free
  • Certified by the vegan society
  • Used in professional treatments
Experts Recommended

Helps to strengthen the skin barrier to prevent any redness flare-ups.

CHARLOTTE BITMEAD
Senior Beauty Writer - Cosmopolitan

Reduced my redness to the point where I sometimes forget to apply it.

KIRSTEN L
Verified Medik8 Customer

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Reviews

Frequently Asked Questions

Can Calmwise Serum be used to treat rosacea or eczema?
As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as rosacea or eczema. We would recommend discussing the ingredients with your doctor or dermatologist before use.
How and when should I apply Calmwise Serum?
You can apply Calmwise Serum every morning and/or evening - after cleansing but before moisturiser. When applying the morning, be sure to follow with a sunscreen.
Can I layer Calmwise Serum with Hydr8 B5 Intense?
Yes, you can. As Hydr8 B5 Intense is water-based, it would be applied before Calmwise Serum, which is oil-based.
Calmwise™ Serum